￼Nanotechnologies deal with the exploitation of the particular properties of matter defined at the scale of nanometers. Nanotechnologies are promising exciting developments in all fields of human activity: agriculture, food technologies, physics, engineering, chemistry, medicine, and more. But do we understand the benefits and the risks of these nanomaterials and nano- technologies? For a more safe use of nanotechnologies to obtain goods and services, is ne- cessary to start from the very beginning and to be “safe by design”? The 3rd“Parma” NANO- DAY will provide answers to these questions.