Analytical Chemistry, Cultural Heritage, Inorganic Chemistry and Crystallography Unit
The members of the Unit are involved in the following main areas of research (refer to the individual website for further information).
Design, preparation and characterization, also by means of X-ray (powders and single crystal) and neutron diffraction techniques, of coordination polymers characterized by microporous supramolecular structures, shape memory magnetic intermetallic materials with magnetocaloric properties, multiferroic oxides and hybrid structures with unconventional electrical properties. Crystal engineering of solvates, polymorphs and co-crystals and of organic / inorganic responsive materials able to include and release chemical species of interest. Synthesis, preparation and characterization of nanostructured functional materials, useful for preserving, strengthening and protecting artefacts against biotic and abiotic degradation, and for the treatment of organic and inorganic pollutants in water. X-ray structural investigations and modeling of organometallic and coordination compounds aimed at defining new synthetic methodologies and at understanding of reaction mechanisms.
Study of the balance of formation of metal complexes in solution. Chemistry of metallacrowns. Study of copper complexes as new antiproliferative / antitumor agents. Study of the interactions of copper ions with metallopeptides de novo designed, and its role in neurodegenerative diseases (Parkinson, Alzheimer). Coordination compounds of the first transition series, in particular thiosemicarbazones, and photoactivable Ru complexes with antitumor, antiviral, antibacterial and antifungal / antiaflatoxigenic properties.
Development and validation of innovative analytical methods based on chromatographic, electrophoretic and mass spectrometry techniques, in order to characterize and control the quality and safety of food products. Evaluation of markers linked to the traceability of a product or connected to the technological production processes. Identification and evaluation of the presence of active ingredients in plant products with particular attention to nutraceutical substances and to the stability of the molecules of interest during extraction and processing. Development and characterization of new materials for the realization of innovative active packaging systems with antioxidant, antimicrobial and antifungal properties.