The research activity in the field of organic synthesis is mainly focused on the development of new synthetic methods, involving the design of new (heterogeneous) catalysts and eco-compatible processes with greater sustainability. The synthetic methodologies are also used for the development of 'engineered' molecular systems: development of molecular machines and devices, synthesis and study of multivalent supramolecular systems for bio-nanotechnologies, for delivery of drugs and DNA binding molecules, design and production of functional polymeric materials, such as vitrimers and self-diagnostic polymers. The design and production of functional molecules find important applications in systems for the treatment of radioactive wastewaters, for innovations in the fields of lubricants, organic photovoltaics and organic LEDs, in the creation of new structural polymeric materials, in the production of inorganic-organic hybrid nanostructures for biomedical applications and for the regulation of gene expression, to cite just a few examples. A cross-sectoral research area with applications in food and environmental fields and clinical diagnostics is represented by the development and validation of innovative biosensors and genosensors. Fundamental theoretical and computational studies are aimed at understanding the electronic structure, properties and reactive as well as non-reactive processes in molecular systems and functional molecular materials. These studies are complementary to advanced techniques of optical spectroscopy (fluorescence, microRaman, FT-IR, two photons) for the study of chromophores and organic fluorophores in solution, for biomedical applications and for the study of functional molecular materials. In addition, a line aimed at the study of inorganic luminescent materials for applications in various sectors such as solid state lasers, phosphors for lighting and LEDs, and diagnostics is active.